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Southeast Asian J Trop Med Public Health ; 2003 ; 34 Suppl 3(): 150-1
Article in English | IMSEAR | ID: sea-34279

ABSTRACT

Use of a third generation TSH assay enabled extremely low values of TSH to be detected through newborn screening. The use of a supplemental free thyroxine improved testing specificity. The hypothyroidism observed is believed to be secondary to suppression of the hypothalamic-pituitary-thyroid axis by placentally transferred maternal thyroxine.


Subject(s)
Congenital Hypothyroidism , Female , Fetal Blood , Hematologic Tests , Humans , Hypothyroidism/diagnosis , Infant, Newborn , Infectious Disease Transmission, Vertical/prevention & control , Neonatal Screening/methods , Pregnancy , Pregnancy Complications/blood , Sensitivity and Specificity , Thyrotoxicosis/blood , Thyrotropin/blood , Thyroxine/administration & dosage
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